POL Scientific, LLC is an open access publisher specializing in the publication of basic research and medical journals covering a diverse spectrum of life sciences and medicine for the benefit of humanity. Our leading journals include: 1) Journal of Biological Methods (ISSN: 2326-9901), committed to publish innovative biological protocols and techniques; 2) Bladder (ISSN: 2327-2120), a medical journal dedicated to publishing research on bladder biology and disease. We are committed to support the scientific community by publishing impactful research and enhancing communication among scientists. At POL Scientific, we are continuously looking for ways to accelerate scientific progress and to strive for transparency and open communication, making knowledge freely accessible without barrier.
Latest articles from journals we publish
- A simple and robust cell-based assay for the discovery of novel cytokinesis inhibitors September 17, 2020Cytokinesis is the last step of mitotic cell division that separates the cytoplasm of dividing cells. Small molecule inhibitors targeting either the elements of the regulatory pathways controlling cytokinesis, or the terminal effectors have been of interest as potential drug candidates for the treatment of various diseases. Here we present a detailed protocol for a […]
- An in vitro model of hepatic steatosis using lipid loaded induced pluripotent stem cell derived hepatocyte like cells July 22, 2020Hepatic steatosis is a metabolic disease, characterized by selective and progressive accumulation of lipids in liver, leading to progressive non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and cirrhosis. The existing in vitro models of hepatic steatosis to elucidate the molecular mechanisms behind the onset of hepatic steatosis and to profile small molecule modulators uses […]
- A 2D and 3D melanogenesis model with human primary cells induced by tyrosine July 6, 2020Research on melanogenesis, its regulation in health and disease, and the discovery of new molecules with pigmenting and depigmenting activities use different models. Here we standardize a protocol based on previous ones using primary human melanocytes and keratinocytes in co-cultures, in which melanogenesis was induced under mild conditions by the addition of tyrosine plus ammonium […]
- Malakoplakia, a malignant mimic September 2, 2020Malakoplakia is a chronic inflammatory condition that affects multiple systems, most commonly the urogenital tract. Its clinical presentation is often non-specific, but is typically characterized by recurrent urinary tract infections and haematuria. We report a rare case of intravesical malakoplakia mimicking an aggressive transitional cell carcinoma both in its clinical presentation and in its macroscopic […]