POL Scientific, LLC is an open access publisher specializing in the publication of basic research and medical journals covering a diverse spectrum of life sciences and medicine for the benefit of humanity. Our leading journals include: 1) Journal of Biological Methods (ISSN: 2326-9901), committed to publish innovative biological protocols and techniques; 2) Bladder (ISSN: 2327-2120), a medical journal dedicated to publishing research on bladder biology and disease. We are committed to support the scientific community by publishing impactful research and enhancing communication among scientists. At POL Scientific, we are continuously looking for ways to accelerate scientific progress and to strive for transparency and open communication, making knowledge freely accessible without barrier.
Latest articles from journals we publish
- Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma September 17, 2019Microinjection is a common embryological technique used for many types of experiments, including lineage tracing, manipulating gene expression, or genome editing. Injectable reagents include mRNA overexpression, mis-expression, or dominant-negative experiments to examine a gene of interest, a morpholino antisense oligo to prevent translation of an mRNA or spliceoform of interest and CRISPR-Cas9 reagents. Thus, the […]
- FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes September 3, 2019High-impact journals are promoting transparency of data. Modern scientific methods can be automated and produce disparate samples sizes. In many cases, it is desirable to retain identical or pre-defined sample sizes between replicates or groups. However, choosing which subset of originally acquired data that best matches the entirety of the data set without introducing bias […]
- The answer depends on the question: Optimal conditions for western blot characterization of muscle collagen type 1 depends on desired isoform August 15, 2019Fibrillar collagen type 1 is the most abundant type of collagen within the body and is a critical component of extracellular infrastructure. In order to assess collagen synthesis and extracellular accumulation in fibrotic disorders, improved methods are needed to detect changes in procollagen versus mature collagen at the protein level. Using Western blot methodology, we […]
- In vivo measurement of enhanced agouti-related peptide release in the paraventricular nucleus of the hypothalamus through Gs activation of agouti-related peptide neurons July 4, 2019Agouti-related peptide (AgRP) neurons of the hypothalamus play a role in hunger-triggered food intake, stability of body weight, and long-term energy balance. A recent study showed that activation of the Gs-linked G protein-coupled receptors (GCPR) expressed by hypothalamic AgRP neurons promotes a sustained increase in food intake. Enhanced AgRP release has been the postulated underlying […]
- Purinergic P2X7 receptors as therapeutic targets in interstitial cystitis/bladder pain syndrome; key role of ATP signaling in inflammation April 8, 2019Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic lower urinary tract condition. Patients with IC/BPS suffer from debilitating pain and urinary urgency. The underlying etiology of IC/BPS is unknown and as such current treatments are mostly symptomatic with no real cure. Many theories have been proposed to describe the etiology of IC/BPS, but this review […]